Nub1-KO 基因敲除小鼠

1. Sendo, Sho, Machado, Camilla R L, Boyle, David L, Wang, Wei, Firestein, Gary S. 2024. Dysregulated NUB1 and Neddylation Enhances Rheumatoid Arthritis Fibroblast-Like Synoviocyte Inflammatory Responses. In Arthritis & rheumatology (Hoboken, N.J.), 76, 1252-1262. doi:10.1002/art.42856. https://pubmed.ncbi.nlm.nih.gov/38566346/

2. Tang, Rong, Jin, Peng, Shen, Chanjuan, Ding, Xiang, Zhong, Yong. 2023. Single-cell RNA sequencing reveals the transcriptomic landscape of kidneys in patients with ischemic acute kidney injury. In Chinese medical journal, 136, 1177-1187. doi:10.1097/CM9.0000000000002679. https://pubmed.ncbi.nlm.nih.gov/37083129/

3. Tanji, Kunikazu, Miki, Yasuo, Maruyama, Atsushi, Kamitani, Tetsu, Wakabayashi, Koichi. 2016. The role of NUB1 in α-synuclein degradation in Lewy body disease model mice. In Biochemical and biophysical research communications, 470, 635-642. doi:10.1016/j.bbrc.2016.01.093. https://pubmed.ncbi.nlm.nih.gov/26797281/

4. Vodicka, Petr, Chase, Kathryn, Iuliano, Maria, Aronin, Neil, DiFiglia, Marian. . Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice. In Journal of Huntington's disease, 5, 163-74. doi:10.3233/JHD-160195. https://pubmed.ncbi.nlm.nih.gov/27314618/

5. Tanji, Kunikazu, Tanaka, Tomoaki, Mori, Fumiaki, Wakabayashi, Koichi, Kamitani, Tetsu. . NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1. In The American journal of pathology, 169, 553-65. doi:. https://pubmed.ncbi.nlm.nih.gov/16877356/

6. Lu, Boxun, Al-Ramahi, Ismael, Valencia, Antonio, Botas, Juan, Palacino, James. 2013. Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance. In Nature neuroscience, 16, 562-70. doi:10.1038/nn.3367. https://pubmed.ncbi.nlm.nih.gov/23525043/

7. Kanaya, Koichi, Sohocki, Melanie M, Kamitani, Tetsu. . Abolished interaction of NUB1 with mutant AIPL1 involved in Leber congenital amaurosis. In Biochemical and biophysical research communications, 317, 768-73. doi:. https://pubmed.ncbi.nlm.nih.gov/15081406/

8. Zhang, Dongdong, Wu, Pei, Zhang, Zhe, Tan, Yuen, Xu, Huimian. 2020. Overexpression of negative regulator of ubiquitin-like proteins 1 (NUB1) inhibits proliferation and invasion of gastric cancer cells through upregulation of p27Kip1 and inhibition of epithelial-mesenchymal transition. In Pathology, research and practice, 216, 153002. doi:10.1016/j.prp.2020.153002. https://pubmed.ncbi.nlm.nih.gov/32703484/

9. Tanji, Kunikazu, Mori, Fumiaki, Kito, Katsumi, Kamitani, Tetsu, Wakabayashi, Koichi. . Synphilin-1-binding protein NUB1 is colocalized with nonfibrillar, proteinase K-resistant α-synuclein in presynapses in Lewy body disease. In Journal of neuropathology and experimental neurology, 70, 879-89. doi:10.1097/NEN.0b013e3182303745. https://pubmed.ncbi.nlm.nih.gov/21937912/