Pycr2-KO 基因敲除小鼠

1. Shao, Zheng, Lu, Lingling, Cui, Yongshi, Chen, Jv, Situ, Yongli. . PYCR in Kidney Renal Papillary Cell Carcinoma: Expression, Prognosis, Gene Regulation Network, and Regulation Targets. In Frontiers in bioscience (Landmark edition), 27, 336. doi:10.31083/j.fbl2712336. https://pubmed.ncbi.nlm.nih.gov/36624948/

2. Sager, Gunes, Türkyilmaz, Ayberk, Günbey, Hediye Pınar, Ozhelvaci, Fatih, Akin, Yasemin. 2023. Pyrroline-5-carboxylate reductase 2 (PYCR2) deficiency causes hereditary spastic paraplaegia in late childhood. In European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 44, 51-56. doi:10.1016/j.ejpn.2023.04.002. https://pubmed.ncbi.nlm.nih.gov/37141741/

3. Wang, Sitong, Gu, Linaer, Huang, Lili, Liu, Zhuqing, Xu, Qing. 2021. The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis. In Biochemical and biophysical research communications, 572, 20-26. doi:10.1016/j.bbrc.2021.07.084. https://pubmed.ncbi.nlm.nih.gov/34332325/

4. Zaki, Maha S, Bhat, Gifty, Sultan, Tipu, Marin-Valencia, Isaac, Gleeson, Joseph G. 2016. PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive. In Annals of neurology, 80, 59-70. doi:10.1002/ana.24678. https://pubmed.ncbi.nlm.nih.gov/27130255/