Fundc2-KO 基因敲除小鼠

1. Yin, Liyang, Cao, Renxian, Liu, Zhuoqing, Zu, Xuyu, Shen, Yingying. . FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway. In Acta biochimica et biophysica Sinica, 55, 1770-1783. doi:10.3724/abbs.2023142. https://pubmed.ncbi.nlm.nih.gov/37700593/

2. Ma, Qi, Zhu, Chongzhuo, Zhang, Weilin, Liu, Junling, Chen, Quan. 2018. Mitochondrial PIP3-binding protein FUNDC2 supports platelet survival via AKT signaling pathway. In Cell death and differentiation, 26, 321-331. doi:10.1038/s41418-018-0121-8. https://pubmed.ncbi.nlm.nih.gov/29786068/

3. Deng, Xinxian, Fang, He, Pathak, Asha, Hisama, Fuki M, Liu, Yajuan J. 2020. Deletion of FUNDC2 and CMC4 on Chromosome Xq28 Is Sufficient to Cause Hypergonadotropic Hypogonadism in Men. In Frontiers in genetics, 11, 557341. doi:10.3389/fgene.2020.557341. https://pubmed.ncbi.nlm.nih.gov/33193636/

4. Sheen, Campbell R, Jewell, Ursula R, Morris, Christine M, Smith, Mark P, Chen, Jian-Min. . Double complex mutations involving F8 and FUNDC2 caused by distinct break-induced replication. In Human mutation, 28, 1198-206. doi:. https://pubmed.ncbi.nlm.nih.gov/17683067/