Fars2-KO 基因敲除小鼠

1. Li, Bowen, Liu, Fangfang, Chen, Xihui, Chen, Kun, Wu, Yuanming. 2024. FARS2 Deficiency Causes Cardiomyopathy by Disrupting Mitochondrial Homeostasis and the Mitochondrial Quality Control System. In Circulation, 149, 1268-1284. doi:10.1161/CIRCULATIONAHA.123.064489. https://pubmed.ncbi.nlm.nih.gov/38362779/

2. Chen, Xihui, Liu, Fangfang, Li, Bowen, Wu, YuanMing, Chen, Kun. 2022. Neuropathy-associated Fars2 deficiency affects neuronal development and potentiates neuronal apoptosis by impairing mitochondrial function. In Cell & bioscience, 12, 103. doi:10.1186/s13578-022-00838-y. https://pubmed.ncbi.nlm.nih.gov/35794642/

3. Cho, Jae So, Kim, Seung Hyo, Kim, Ha Young, Kim, Ki Joong, Lim, Byung Chan. 2016. FARS2 mutation and epilepsy: Possible link with early-onset epileptic encephalopathy. In Epilepsy research, 129, 118-124. doi:10.1016/j.eplepsyres.2016.11.022. https://pubmed.ncbi.nlm.nih.gov/28043061/

4. Sahai, Supreet K, Steiner, Rebecca E, Au, Margaret G, Ibba, Michael, Pierson, Tyler M. 2018. FARS2 mutations presenting with pure spastic paraplegia and lesions of the dentate nuclei. In Annals of clinical and translational neurology, 5, 1128-1133. doi:10.1002/acn3.598. https://pubmed.ncbi.nlm.nih.gov/30250868/

5. Yang, Ying, Liu, Wei, Fang, Zhipeng, Wang, Enduo, Wu, Yuanming. 2015. A Newly Identified Missense Mutation in FARS2 Causes Autosomal-Recessive Spastic Paraplegia. In Human mutation, 37, 165-9. doi:10.1002/humu.22930. https://pubmed.ncbi.nlm.nih.gov/26553276/