Oma1-KO 基因敲除小鼠

1. Rivera-Mejías, Pablo, Narbona-Pérez, Álvaro Jesús, Hasberg, Lidwina, Lavandero, Sergio, Langer, Thomas. 2023. The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage. In Cell reports, 42, 112332. doi:10.1016/j.celrep.2023.112332. https://pubmed.ncbi.nlm.nih.gov/37002921/

2. Arakawa, Takumi, Sugaya, Hajime, Katsuyama, Takaya, Kitazaki, Kazuyoshi, Kubo, Tomohiko. 2019. How did a duplicated gene copy evolve into a restorer-of-fertility gene in a plant? The case of Oma1. In Royal Society open science, 6, 190853. doi:10.1098/rsos.190853. https://pubmed.ncbi.nlm.nih.gov/31827833/

3. Wai, Timothy, García-Prieto, Jaime, Baker, Michael J, Ibañez, Borja, Langer, Thomas. . Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. In Science (New York, N.Y.), 350, aad0116. doi:10.1126/science.aad0116. https://pubmed.ncbi.nlm.nih.gov/26785494/

4. Franchino, Camilla Aurora, Brughera, Martina, Baderna, Valentina, Scalais, Emmanuel, Maltecca, Francesca. . Sustained OMA1-mediated integrated stress response is beneficial for spastic ataxia type 5. In Brain : a journal of neurology, 147, 1043-1056. doi:10.1093/brain/awad340. https://pubmed.ncbi.nlm.nih.gov/37804316/