Myo7a-KO 基因敲除小鼠

1. Schott, Juliane W, Huang, Peixin, Morgan, Michael, Schambach, Axel, Staecker, Hinrich. 2023. Third-generation lentiviral gene therapy rescues function in a mouse model of Usher 1B. In Molecular therapy : the journal of the American Society of Gene Therapy, 31, 3502-3519. doi:10.1016/j.ymthe.2023.10.018. https://pubmed.ncbi.nlm.nih.gov/37915173/

2. Gilmore, W Blake, Hultgren, Nan W, Chadha, Abhishek, Canto-Soler, M Valeria, Williams, David S. 2023. Expression of two major isoforms of MYO7A in the retina: Considerations for gene therapy of Usher syndrome type 1B. In Vision research, 212, 108311. doi:10.1016/j.visres.2023.108311. https://pubmed.ncbi.nlm.nih.gov/37586294/

3. O'Connor, Andrew P, Amariutei, Ana E, Zanella, Alice, Safieddine, Saaid, Marcotti, Walter. 2024. In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells. In JCI insight, 9, . doi:10.1172/jci.insight.182138. https://pubmed.ncbi.nlm.nih.gov/39641274/