Zcchc8-KO 基因敲除小鼠

1. Gable, Dustin L, Gaysinskaya, Valeriya, Atik, Christine C, Florea, Liliana, Armanios, Mary. 2019. ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation. In Genes & development, 33, 1381-1396. doi:10.1101/gad.326785.119. https://pubmed.ncbi.nlm.nih.gov/31488579/

2. Mito, Jeffrey K, Weber, Margaret C, Corbin, Alexandra, Murphy, George F, Zon, Leonard I. 2022. Modeling Spitz melanoma in zebrafish using sequential mutagenesis. In Disease models & mechanisms, 15, . doi:10.1242/dmm.049452. https://pubmed.ncbi.nlm.nih.gov/36017742/

3. Wu, You, Liu, Wenqiang, Chen, Jiayu, Gao, Yawei, Gao, Shaorong. . Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells. In Cell reports, 29, 2461-2472.e6. doi:10.1016/j.celrep.2019.10.055. https://pubmed.ncbi.nlm.nih.gov/31747613/

4. Coccé, Mariela C, Mardin, Balca R, Bens, Susanne, Alonso, Cristina N, Gallego, Marta S. 2016. Identification of ZCCHC8 as fusion partner of ROS1 in a case of congenital glioblastoma multiforme with a t(6;12)(q21;q24.3). In Genes, chromosomes & cancer, 55, 677-87. doi:10.1002/gcc.22369. https://pubmed.ncbi.nlm.nih.gov/27121553/