Ccng1-KO 基因敲除小鼠

1. Xu, Ying, Zhang, Qing, Miao, Chunying, Yang, Xingsheng, Kong, Beihua. 2018. CCNG1 (Cyclin G1) regulation by mutant-P53 via induction of Notch3 expression promotes high-grade serous ovarian cancer (HGSOC) tumorigenesis and progression. In Cancer medicine, 8, 351-362. doi:10.1002/cam4.1812. https://pubmed.ncbi.nlm.nih.gov/30565428/

2. Lin, Tao, Ma, Quanping, Zhang, Yuefeng, Yan, Jiapeng, Gao, Changhong. 2017. MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1. In Oncology letters, 15, 1067-1071. doi:10.3892/ol.2017.7389. https://pubmed.ncbi.nlm.nih.gov/29399167/

3. Chen, Ye, Yan, Rui, Li, Bo, Song, Wenyu, Zhu, Chunling. 2020. Silencing CCNG1 protects MPC-5 cells from high glucose-induced proliferation-inhibition and apoptosis-promotion via MDM2/p53 signaling pathway. In International urology and nephrology, 52, 581-593. doi:10.1007/s11255-020-02383-4. https://pubmed.ncbi.nlm.nih.gov/32016904/

4. Chen, Yuzhong, Liang, Wanqing, Du, Jun, Liang, Rongrui, Tao, Min. 2022. PRMT6 functionally associates with PRMT5 to promote colorectal cancer progression through epigenetically repressing the expression of CDKN2B and CCNG1. In Experimental cell research, 422, 113413. doi:10.1016/j.yexcr.2022.113413. https://pubmed.ncbi.nlm.nih.gov/36400182/