Thpo-KO 基因敲除小鼠

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2. Houwing, Maite E, Koopman-Coenen, Eva A, Kersseboom, Rogier, Michel Zwaan, C, van den Heuvel-Eibrink, Marry M. 2015. Somatic thrombopoietin (THPO) gene mutations in childhood myeloid leukemias. In International journal of hematology, 102, 140-3. doi:10.1007/s12185-015-1759-3. https://pubmed.ncbi.nlm.nih.gov/25728710/

3. Alasmari, Badriah G, Elzubair, Khalid, Alquraishi, Ali, Elzubair, Lina, Al Tala, Saeed. 2024. A Rare THPO Gene Mutation in a Saudi Female Child: A Case Report and Literature Review. In Cureus, 16, e70513. doi:10.7759/cureus.70513. https://pubmed.ncbi.nlm.nih.gov/39479124/

4. Capaci, Valeria, Adam, Etai, Bar-Joseph, Ifat, Pecci, Alessandro, Savoia, Anna. 2023. Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia. In Haematologica, 108, 1385-1393. doi:10.3324/haematol.2022.281392. https://pubmed.ncbi.nlm.nih.gov/36226497/

5. Kimura, Hiroyuki, Onozawa, Masahiro, Matsukawa, Toshihiro, Kondo, Takeshi, Teshima, Takanori. 2024. Relative impact of THPO mutation causing hereditary thrombocythemia. In Experimental hematology, 134, 104208. doi:10.1016/j.exphem.2024.104208. https://pubmed.ncbi.nlm.nih.gov/38548144/

6. Yang, Lian, Wu, Liangliang, Meng, Panpan, Lin, Qing, Zhang, Yiyue. 2022. Generation of a thrombopoietin-deficient thrombocytopenia model in zebrafish. In Journal of thrombosis and haemostasis : JTH, 20, 1900-1909. doi:10.1111/jth.15772. https://pubmed.ncbi.nlm.nih.gov/35622056/

7. Wang, Xinan, Muramatsu, Hideki, Sakaguchi, Hirotoshi, Takahashi, Yoshiyuki, Kojima, Seiji. 2012. Mutation in the THPO gene is not associated with aplastic anaemia in Japanese children. In British journal of haematology, 158, 553-5. doi:10.1111/j.1365-2141.2012.09185.x. https://pubmed.ncbi.nlm.nih.gov/22686250/

8. Chang, M S, Hsu, R Y, McNinch, J, Copeland, N G, Jenkins, N A. . The gene for murine megakaryocyte growth and development factor (thrombopoietin, Thpo) is located on mouse chromosome 16. In Genomics, 26, 636-7. doi:. https://pubmed.ncbi.nlm.nih.gov/7607698/

9. Bhat, Firdous A, Advani, Jayshree, Khan, Aafaque Ahmad, Keshava Prasad, T S, Chatterjee, Aditi. 2018. A network map of thrombopoietin signaling. In Journal of cell communication and signaling, 12, 737-743. doi:10.1007/s12079-018-0480-4. https://pubmed.ncbi.nlm.nih.gov/30039510/

10. Tracey, C J, Pan, X, Catterson, J H, Hussain, M M, Hartley, P S. . Diurnal expression of the thrombopoietin gene is regulated by CLOCK. In Journal of thrombosis and haemostasis : JTH, 10, 662-9. doi:10.1111/j.1538-7836.2012.04643.x. https://pubmed.ncbi.nlm.nih.gov/22284746/