Rab4a-KO 基因敲除小鼠

1. Huang, Nick, Winans, Thomas, Wyman, Brandon, Banki, Katalin, Perl, Andras. 2024. Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation. In Nature communications, 15, 2598. doi:10.1038/s41467-024-46441-2. https://pubmed.ncbi.nlm.nih.gov/38519468/

2. Karthikeyan, Subbulakshmi, Casey, Patrick J, Wang, Mei. 2022. RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation. In Breast cancer research : BCR, 24, 72. doi:10.1186/s13058-022-01564-6. https://pubmed.ncbi.nlm.nih.gov/36307864/

3. Cao, Guo-Jun, Wang, Di, Zeng, Zhao-Pei, Hu, Chun-Jiu, Xing, Zhi-Fang. . Direct interaction between Rab5a and Rab4a enhanced epidermal growth factor-stimulated proliferation of gastric cancer cells. In World journal of gastrointestinal oncology, 13, 1492-1505. doi:10.4251/wjgo.v13.i10.1492. https://pubmed.ncbi.nlm.nih.gov/34721780/

4. Jackson, Travis C, Kotermanski, Shawn E, Kochanek, Patrick M. 2017. Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons. In Neuroscience, 361, 93-107. doi:10.1016/j.neuroscience.2017.08.014. https://pubmed.ncbi.nlm.nih.gov/28818525/

5. Hudson, N J, Porto-Neto, L, Naval-Sanchez, M, Lyons, R E, Reverter, Antonio. 2021. A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells. In Animal genetics, 52, 275-283. doi:10.1111/age.13054. https://pubmed.ncbi.nlm.nih.gov/33709423/

6. Caza, Tiffany, Wijewardena, Chathura, Al-Rabadi, Laith, Perl, Andras. 2022. Cell type-specific mechanistic target of rapamycin-dependent distortion of autophagy pathways in lupus nephritis. In Translational research : the journal of laboratory and clinical medicine, 245, 55-81. doi:10.1016/j.trsl.2022.03.004. https://pubmed.ncbi.nlm.nih.gov/35288362/

7. Wu, KeShangJing, Liu, QingSong, Long, KeYu, Li, Li, Li, Bin. 2024. Deciphering the role of lipid metabolism-related genes in Alzheimer's disease: a machine learning approach integrating Traditional Chinese Medicine. In Frontiers in endocrinology, 15, 1448119. doi:10.3389/fendo.2024.1448119. https://pubmed.ncbi.nlm.nih.gov/39507054/

8. Dransfeld, O, Uphues, I, Sasson, S, Joost, H G, Eckel, J. . Regulation of subcellular distribution of GLUT4 in cardiomyocytes: Rab4A reduces basal glucose transport and augments insulin responsiveness. In Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 108, 26-36. doi:. https://pubmed.ncbi.nlm.nih.gov/10768829/