Batf-KO 基因敲除小鼠

1. Zhang, Xingying, Zhang, Chenze, Qiao, Miaomiao, Han, Weidong, Wang, Haoyi. 2022. Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells. In Cancer cell, 40, 1407-1422.e7. doi:10.1016/j.ccell.2022.09.013. https://pubmed.ncbi.nlm.nih.gov/36240777/

2. Shan, Feng, Cillo, Anthony R, Cardello, Carly, Benos, Panayiotis V, Vignali, Dario A A. 2023. Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells. In Science immunology, 8, eadf6717. doi:10.1126/sciimmunol.adf6717. https://pubmed.ncbi.nlm.nih.gov/37713508/

3. Kumar, Bijender, Singh, Anand, Basar, Rafet, Rezvani, Katayoun, Daher, May. 2024. BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. In Science translational medicine, 16, eadp0004. doi:10.1126/scitranslmed.adp0004. https://pubmed.ncbi.nlm.nih.gov/39259809/