Reg2-KO 基因敲除小鼠

1. Frederick, D L, Tatchell, K. . The REG2 gene of Saccharomyces cerevisiae encodes a type 1 protein phosphatase-binding protein that functions with Reg1p and the Snf1 protein kinase to regulate growth. In Molecular and cellular biology, 16, 2922-31. doi:. https://pubmed.ncbi.nlm.nih.gov/8649403/

2. Li, Qing, Li, Bing, Miao, Xiaoliang, Gao, Zu-Hua, Liu, Jun-Li. . Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet-Induced Obesity. In Endocrinology, 158, 1634-1644. doi:10.1210/en.2016-1551. https://pubmed.ncbi.nlm.nih.gov/28009527/

3. Tebar, L A, Géranton, S M, Parsons-Perez, C, Raivich, G, Hunt, S P. 2008. Deletion of the mouse RegIIIbeta (Reg2) gene disrupts ciliary neurotrophic factor signaling and delays myelination of mouse cranial motor neurons. In Proceedings of the National Academy of Sciences of the United States of America, 105, 11400-5. doi:10.1073/pnas.0711978105. https://pubmed.ncbi.nlm.nih.gov/18678917/

4. Lieu, Hanh-Tu, Simon, Marie-Thérèse, Nguyen-Khoa, Thao, Bréchot, Christian, Christa, Laurence. . Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice. In Hepatology (Baltimore, Md.), 44, 1452-64. doi:. https://pubmed.ncbi.nlm.nih.gov/17133485/