Pcdhgc3-KO 基因敲除小鼠

1. Cubiella, Tamara, Celada, Lucía, San-Juan-Guardado, Jaime, Valdés, Nuria, Chiara, María-Dolores. 2024. PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas. In The Journal of pathology, 263, 418-428. doi:10.1002/path.6291. https://pubmed.ncbi.nlm.nih.gov/38795318/

2. Bernardo-Castiñeira, Cristóbal, Valdés, Nuria, Celada, Lucía, Suarez, Carlos, Chiara, María-Dolores. . Epigenetic Deregulation of Protocadherin PCDHGC3 in Pheochromocytomas/Paragangliomas Associated With SDHB Mutations. In The Journal of clinical endocrinology and metabolism, 104, 5673-5692. doi:10.1210/jc.2018-01471. https://pubmed.ncbi.nlm.nih.gov/31216007/

3. Feldheim, Jonas, Wend, David, Lauer, Mara J, Hagemann, Carsten, Burek, Malgorzata. 2022. Protocadherin Gamma C3 (PCDHGC3) Is Strongly Expressed in Glioblastoma and Its High Expression Is Associated with Longer Progression-Free Survival of Patients. In International journal of molecular sciences, 23, . doi:10.3390/ijms23158101. https://pubmed.ncbi.nlm.nih.gov/35897674/

4. Meltzer, Shan, Boulanger, Katelyn C, Chirila, Anda M, Weiner, Joshua A, Ginty, David D. 2023. γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons. In Neuron, 111, 1776-1794.e10. doi:10.1016/j.neuron.2023.03.012. https://pubmed.ncbi.nlm.nih.gov/37028432/

5. Dallosso, A R, Øster, B, Greenhough, A, Andersen, C L, Malik, K. 2012. Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways. In Oncogene, 31, 4409-19. doi:10.1038/onc.2011.609. https://pubmed.ncbi.nlm.nih.gov/22249255/

6. Mancia Leon, Walter R, Spatazza, Julien, Rakela, Benjamin, Stryker, Michael P, Alvarez-Buylla, Arturo. 2020. Clustered gamma-protocadherins regulate cortical interneuron programmed cell death. In eLife, 9, . doi:10.7554/eLife.55374. https://pubmed.ncbi.nlm.nih.gov/32633719/

7. Wang, Yi, Cheng, Hong, Zeng, Tengyue, Xing, Qianwei, Zhu, Bingye. 2022. A novel 17 apoptosis-related genes signature could predict overall survival for bladder cancer and its associations with immune infiltration. In Heliyon, 8, e11343. doi:10.1016/j.heliyon.2022.e11343. https://pubmed.ncbi.nlm.nih.gov/36387445/

8. Dilling, Christina, Roewer, Norbert, Förster, Carola Y, Burek, Malgorzata. 2017. Multiple protocadherins are expressed in brain microvascular endothelial cells and might play a role in tight junction protein regulation. In Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37, 3391-3400. doi:10.1177/0271678X16688706. https://pubmed.ncbi.nlm.nih.gov/28094605/