Dhcr24-KO 基因敲除小鼠

1. Shen, Yajie, Zhou, Jingqi, Nie, Kui, Tam, Wayne, Ma, Jiao. . Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas. In Blood, 139, 73-86. doi:10.1182/blood.2021012327. https://pubmed.ncbi.nlm.nih.gov/34624089/

2. Di Stasi, Delia, Vallacchi, Viviana, Campi, Valentina, Pierotti, Marco A, Rodolfo, Monica. . DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis. In International journal of cancer, 115, 224-30. doi:. https://pubmed.ncbi.nlm.nih.gov/15688385/

3. Mirza, Rusella, Hayasaka, Shizu, Takagishi, Yoshiko, Murata, Yoshiharu, Seo, Hisao. . DHCR24 gene knockout mice demonstrate lethal dermopathy with differentiation and maturation defects in the epidermis. In The Journal of investigative dermatology, 126, 638-47. doi:. https://pubmed.ncbi.nlm.nih.gov/16410790/

4. Li, Zhao, Yu, Shenghui, Li, Lin, Sun, Xiaochuan, Yan, Jin. . TREM2 alleviates white matter injury after traumatic brain injury in mice might be mediated by regulation of DHCR24/LXR pathway in microglia. In Clinical and translational medicine, 14, e1665. doi:10.1002/ctm2.1665. https://pubmed.ncbi.nlm.nih.gov/38649789/