Otud3-KO 基因敲除小鼠

1. Zhou, Na, Qi, Hailong, Liu, Junjun, Song, Yongfeng, Yin, Yuxin. 2022. Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses. In Cell metabolism, 34, 1023-1041.e8. doi:10.1016/j.cmet.2022.05.005. https://pubmed.ncbi.nlm.nih.gov/35675826/

2. Wang, Meng, Li, Yue, Xiao, Yunyun, Lin, Chuyong, Song, Libing. 2021. Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer. In Nature communications, 12, 7006. doi:10.1038/s41467-021-27348-8. https://pubmed.ncbi.nlm.nih.gov/34853315/

3. Cai, Xiaolian, Zhou, Ziwen, Zhu, Junji, Chen, Xiaoyun, Xiao, Wuhan. . Opposing effects of deubiquitinase OTUD3 in innate immunity against RNA and DNA viruses. In Cell reports, 39, 110920. doi:10.1016/j.celrep.2022.110920. https://pubmed.ncbi.nlm.nih.gov/35675783/

4. Xie, Peiyi, Chen, Yanglin, Zhang, Hongfei, Hao, Liang, Huang, Da. 2021. The deubiquitinase OTUD3 stabilizes ACTN4 to drive growth and metastasis of hepatocellular carcinoma. In Aging, 13, 19317-19338. doi:10.18632/aging.203293. https://pubmed.ncbi.nlm.nih.gov/34380780/

5. Liu, Yi-Zhen, Du, Xi-Xun, Zhao, Qi-Qi, Jiao, Qian, Jiang, Hong. . The expression change of OTUD3-PTEN signaling axis in glioma cells. In Annals of translational medicine, 8, 490. doi:10.21037/atm.2020.03.51. https://pubmed.ncbi.nlm.nih.gov/32395534/