智鼠故事 
Sting1-KO 基因敲除小鼠
复苏/繁育服务
产品名称
Sting1-KO 基因敲除小鼠
产品编号
S-KO-13962
品系全称
C57BL/6NCya-Sting1em1/Cya
品系背景
C57BL/6NCya
品系编号
KOCMP-72512-Sting1-B6N-VA
品系状态
使用本品系发表的文献需注明： Sting1-KO 基因敲除小鼠 mice (Strain S-KO-13962) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
ERIS，MPYS，Mita，STING，Tmem173，STING-beta，2610307O08Rik
NCBI ID
染色体号
Chr 18
NCBI RefSeq
NM_028261
Ensembl ID
ENSMUST00000115728
修饰方式
全身性基因敲除
靶向范围
Exon 2~8
敲除长度
~5.6 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:1919762Mice homozygous for a knock-out allele exhibit increased susceptibility to viral infection and abnormal innate immunity. Mice homozygous for an ENU-induced allele exhibit altered response to bacterial and viral infection. Male mice homozygous for a null allele exhibit normal fertility.
发表文献
Cell Death Discovery
2024-07-07
Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice
Journal of Ethnopharmacology
2024-01-30
QFAE-nB alleviates pulmonary fibrosis by inhibiting the STING pathway in mice
Nature Cell Biology
2024-01-22
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders
Cell Communication and Signaling
2023-12-21
Hyperglycemia-induced STING signaling activation leads to aortic endothelial injury in diabetes
ISME Journal
2023-11-10
Ginsenoside Rg3 enriches SCFA-producing commensal bacteria to confer protection against enteric viral infection via the cGAS-STING-type I IFN axis
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