Mir200c-KO 基因敲除小鼠

1. Wang, Xiaoying, He, Xiangfeng, Zhao, Fengshu, Cai, Kai, Dou, Jun. 2014. Regulation gene expression of miR200c and ZEB1 positively enhances effect of tumor vaccine B16F10/GPI-IL-21 on inhibition of melanoma growth and metastasis. In Journal of translational medicine, 12, 68. doi:10.1186/1479-5876-12-68. https://pubmed.ncbi.nlm.nih.gov/24625224/

2. Bertoli, Gloria, Cava, Claudia, Castiglioni, Isabella. 2015. MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer. In Theranostics, 5, 1122-43. doi:10.7150/thno.11543. https://pubmed.ncbi.nlm.nih.gov/26199650/

3. Vad-Nielsen, Johan, Staunstrup, Nicklas Heine, Kjeldsen, Magnus Lindkvist, Sorensen, Boe Sandahl, Nielsen, Anders Lade. 2023. Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells. In Translational lung cancer research, 12, 42-65. doi:10.21037/tlcr-22-507. https://pubmed.ncbi.nlm.nih.gov/36762066/

4. Zhu, Yixiao, Huang, Chengmei, Zhang, Chao, Liao, Wenting, Wang, Xin. 2023. LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation. In Nature communications, 14, 8141. doi:10.1038/s41467-023-43974-w. https://pubmed.ncbi.nlm.nih.gov/38065939/

5. Su, Wenjing, Xu, Miao, Chen, Xueqin, Huang, Lei, Zhou, Qiao. 2015. MiR200c targets IRS1 and suppresses prostate cancer cell growth. In The Prostate, 75, 855-62. doi:10.1002/pros.22968. https://pubmed.ncbi.nlm.nih.gov/25683382/

6. Sui, Hua, Cai, Guo-Xiang, Pan, Shu-Fang, Zhu, Hui-Rong, Li, Qi. 2014. miR200c attenuates P-gp-mediated MDR and metastasis by targeting JNK2/c-Jun signaling pathway in colorectal cancer. In Molecular cancer therapeutics, 13, 3137-51. doi:10.1158/1535-7163.MCT-14-0167. https://pubmed.ncbi.nlm.nih.gov/25205654/

7. Xie, Hanbing, Nie, Ling, Zhang, Mengni, Chen, Ni, Zhou, Qiao. 2019. Suppression of α-methylacyl-coenzyme A racemase by miR200c inhibits prostate adenocarcinoma cell proliferation and migration. In Experimental and therapeutic medicine, 19, 1806-1816. doi:10.3892/etm.2019.8406. https://pubmed.ncbi.nlm.nih.gov/32104236/

8. Ghafouri-Fard, Soudeh, Shoorei, Hamed, Taheri, Mohammad. 2020. miRNA profile in ovarian cancer. In Experimental and molecular pathology, 113, 104381. doi:10.1016/j.yexmp.2020.104381. https://pubmed.ncbi.nlm.nih.gov/31954715/

9. Hannan, Natalie J, Cohen, Paul A, Beard, Sally, Whitehead, Clare, Hui, Lisa. 2021. Transcriptomic analysis of patient plasma reveals circulating miR200c as a potential biomarker for high-grade serous ovarian cancer. In Gynecologic oncology reports, 39, 100894. doi:10.1016/j.gore.2021.100894. https://pubmed.ncbi.nlm.nih.gov/35005155/

10. Liu, Wenwen, Fan, Lihui, Shao, Bo, Zhang, Yang. 2023. STAT3 promotes migration and invasion of cholangiocarcinoma arising from choledochal cyst by transcriptionally inhibiting miR200c through the c-myb/MEK/ERK signaling pathway. In Cellular and molecular biology (Noisy-le-Grand, France), 69, 136-142. doi:10.14715/cmb/2023.69.9.20. https://pubmed.ncbi.nlm.nih.gov/37807322/