Wdr20-KO 基因敲除小鼠

1. Jiang, Li, Qi, Xuxin, Lai, Minshan, Yang, Bo, Cao, Ji. 2024. WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc. In Proceedings of the National Academy of Sciences of the United States of America, 121, e2407904121. doi:10.1073/pnas.2407904121. https://pubmed.ncbi.nlm.nih.gov/39432777/

2. McClurg, Urszula L, Harle, Victoria J, Nabbi, Arash, McCracken, Stuart R C, Robson, Craig N. . Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer. In Oncotarget, 6, 37724-36. doi:10.18632/oncotarget.6075. https://pubmed.ncbi.nlm.nih.gov/26462181/

3. Takahashi, Mika, Tsukamoto, Yoshiyuki, Kai, Tomoki, Matsuura, Keiko, Moriyama, Masatsugu. 2016. Downregulation of WDR20 due to loss of 14q is involved in the malignant transformation of clear cell renal cell carcinoma. In Cancer science, 107, 417-23. doi:10.1111/cas.12892. https://pubmed.ncbi.nlm.nih.gov/26790128/