Agpat2-KO 基因敲除小鼠

1. Peng, Kenan, Chen, Xin, Pei, Kexin, Liu, Gang, Gao, Mingming. 2023. Lipodystrophic gene Agpat2 deficiency aggravates hyperlipidemia and atherosclerosis in Ldlr-/- mice. In Biochimica et biophysica acta. Molecular basis of disease, 1870, 166850. doi:10.1016/j.bbadis.2023.166850. https://pubmed.ncbi.nlm.nih.gov/37591406/

2. Tapia, Pablo J, Figueroa, Ana-María, Eisner, Verónica, Garg, Abhimanyu, Cortés, Víctor. 2020. Absence of AGPAT2 impairs brown adipogenesis, increases IFN stimulated gene expression and alters mitochondrial morphology. In Metabolism: clinical and experimental, 111, 154341. doi:10.1016/j.metabol.2020.154341. https://pubmed.ncbi.nlm.nih.gov/32810486/

3. Sakuma, Ikki, Gaspar, Rafael C, Luukkonen, Panu K, Petersen, Kitt Falk, Shulman, Gerald I. 2023. Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition. In Proceedings of the National Academy of Sciences of the United States of America, 120, e2312666120. doi:10.1073/pnas.2312666120. https://pubmed.ncbi.nlm.nih.gov/38127985/

4. Agarwal, Anil K, Arioglu, Elif, De Almeida, Salome, Barnes, Robert I, Garg, Abhimanyu. 2002. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. In Nature genetics, 31, 21-3. doi:. https://pubmed.ncbi.nlm.nih.gov/11967537/