Cfap418位于小鼠的4号染色体,采用CRISPR/Cas技术,设计sgRNA,通过应用高通量电转受精卵方式,获得Cfap418基因敲除小鼠,性成熟后取精子冻存。
相关疾病:
Bardet-Biedl Syndrome 21
Cone-Rod Dystrophy 16
Retinitis Pigmentosa
Cone-Rod Dystrophy 2
Bardet-Biedl Syndrome
Retinal Disease
Polydactyly
Retinal Degeneration
Myopia
Bardet-Biedl Syndrome 19