Sirt2-KO 基因敲除小鼠

1. Li, Yutong, Bie, Juntao, Song, Chen, You, Fuping, Luo, Jianyuan. 2023. SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1. In EMBO reports, 24, e57500. doi:10.15252/embr.202357500. https://pubmed.ncbi.nlm.nih.gov/37870259/

2. Shen, Yuanyuan, Chen, Liyu, Zhang, Shuijing, Xie, Liquan. 2020. Correlation Between SIRT2 3'UTR Gene Polymorphism and the Susceptibility to Alzheimer's Disease. In Journal of molecular neuroscience : MN, 70, 878-886. doi:10.1007/s12031-020-01513-y. https://pubmed.ncbi.nlm.nih.gov/32124252/

3. Li, Chang, Zhou, Yuning, Rychahou, Piotr, Wang, Qingding, Evers, B Mark. 2020. SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and Differentiation. In Cellular and molecular gastroenterology and hepatology, 10, 43-57. doi:10.1016/j.jcmgh.2020.01.004. https://pubmed.ncbi.nlm.nih.gov/31954883/

4. Geng, Anke, Sun, Jiahui, Tang, Huanyin, Jiang, Ying, Mao, Zhiyong. . SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner. In Nucleic acids research, 52, 5107-5120. doi:10.1093/nar/gkae190. https://pubmed.ncbi.nlm.nih.gov/38554113/

5. Zhang, Xiaomin, Azhar, Gohar, Wei, Jeanne Y. 2017. SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation. In PloS one, 12, e0190011. doi:10.1371/journal.pone.0190011. https://pubmed.ncbi.nlm.nih.gov/29267359/

6. Yang, Shu, Yang, Guangyan, Wang, Xinyu, Kang, Lin, Liang, Zhen. 2023. SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells. In Cell death & disease, 14, 646. doi:10.1038/s41419-023-06169-1. https://pubmed.ncbi.nlm.nih.gov/37777567/

7. Ren, Huihui, Hu, Fuqing, Wang, Dan, Liu, Siyue, Yuan, Gang. 2021. Sirtuin 2 Prevents Liver Steatosis and Metabolic Disorders by Deacetylation of Hepatocyte Nuclear Factor 4α. In Hepatology (Baltimore, Md.), 74, 723-740. doi:10.1002/hep.31773. https://pubmed.ncbi.nlm.nih.gov/33636024/