Fbxl7-KO 基因敲除小鼠

1. Camuzi, Diego, Buexm, Luisa Aguirre, Lourenço, Simone de Queiroz Chaves, Ribeiro Pinto, Luis Felipe, Soares-Lima, Sheila Coelho. 2022. FBXL7 Body Hypomethylation Is Frequent in Tumors from the Digestive and Respiratory Tracts and Is Associated with Risk-Factor Exposure. In International journal of molecular sciences, 23, . doi:10.3390/ijms23147801. https://pubmed.ncbi.nlm.nih.gov/35887149/

2. Moro, Loredana, Simoneschi, Daniele, Kurz, Emma, Hsieh, Jer-Tsong, Pagano, Michele. 2020. Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. In Nature cell biology, 22, 1130-1142. doi:10.1038/s41556-020-0560-6. https://pubmed.ncbi.nlm.nih.gov/32839549/

3. Zhou, Jing, Lin, Yang, Kang, Xiuhua, Zou, Juntao, Xu, Fei. 2023. Hypoxia-mediated promotion of glucose metabolism in non-small cell lung cancer correlates with activation of the EZH2/FBXL7/PFKFB4 axis. In Cell death & disease, 14, 326. doi:10.1038/s41419-023-05795-z. https://pubmed.ncbi.nlm.nih.gov/37179372/

4. Boone, Philip M, Paterson, Scott, Mohajeri, Kiana, Hogan, Benjamin M, Rodan, Lance H. 2019. Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome. In American journal of medical genetics. Part A, 182, 189-194. doi:10.1002/ajmg.a.61392. https://pubmed.ncbi.nlm.nih.gov/31633297/

5. Moro, Loredana, Pagano, Michele. 2020. Epigenetic suppression of FBXL7 promotes metastasis. In Molecular & cellular oncology, 7, 1833698. doi:10.1080/23723556.2020.1833698. https://pubmed.ncbi.nlm.nih.gov/33235922/

6. Liao, Jinzhuang, Qing, Xiang, Li, Xiaoying, Li, Wei, Song, Wei. 2024. TRAF4 regulates ubiquitination-modulated survivin turnover and confers radioresistance. In International journal of biological sciences, 20, 182-199. doi:10.7150/ijbs.87180. https://pubmed.ncbi.nlm.nih.gov/38164179/

7. Wang, Shuai, Zhao, Xunping, Zhu, Shuyuan, Xu, Jiali, Luo, Tao. 2023. F-Box and Leucine-Rich Repeat Protein 7 Is a Prognostic Biomarker and Is Correlated with the Immunosuppressive Microenvironment in Colorectal Cancer. In Genetic testing and molecular biomarkers, 27, 325-338. doi:10.1089/gtmb.2023.0075. https://pubmed.ncbi.nlm.nih.gov/37862037/

8. Kong, Shiqi, Fang, Yanwei, Wang, Bingqian, He, Runzhi, Zhao, Zongmao. 2020. miR-152-5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7. In Journal of cellular and molecular medicine, 24, 4569-4579. doi:10.1111/jcmm.15114. https://pubmed.ncbi.nlm.nih.gov/32150671/

9. Liu, Yuan, Lear, Travis, Iannone, Olivia, Chen, Bill B, Mallampalli, Rama K. 2015. The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin. In The Journal of biological chemistry, 290, 11843-52. doi:10.1074/jbc.M114.629931. https://pubmed.ncbi.nlm.nih.gov/25778398/

10. Keskin, Ozlem, Farzan, Niloufar, Birben, Esra, Vijverberg, Susanne J, Kalayci, Omer. 2019. Genetic associations of the response to inhaled corticosteroids in asthma: a systematic review. In Clinical and translational allergy, 9, 2. doi:10.1186/s13601-018-0239-2. https://pubmed.ncbi.nlm.nih.gov/30647901/