智鼠故事 
Fndc5-KO 基因敲除小鼠
复苏/繁育服务
产品名称
Fndc5-KO 基因敲除小鼠
产品编号
S-KO-09897
品系全称
C57BL/6NCya-Fndc5em1/Cya
品系背景
C57BL/6NCya
品系编号
KOCMP-384061-Fndc5-B6N-VA
品系状态
使用本品系发表的文献需注明： Fndc5-KO 基因敲除小鼠 mice (Strain S-KO-09897) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因全称
fibronectin type III domain containing 5
基因别称
PeP，Pxp，1500001L03Rik
染色体号
Chr 4 (Mouse)
NCBI ID
转录本 ID
NCBI: NM_027402 | Ensembl: ENSMUST00000102600
修饰方式
全身性基因敲除
靶向范围
Exon 2
敲除长度
~0.1 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:1917614Mice homozygous for a knock-out mice exhibit increased trabecular bone mass and bone connectivity density with resistance to ovariectomy-induced osteoporosis. Homozygous KO also increases susceptibility to diet-induced obesity, hepatic steatosis, cardiac hypertrophy and cardiac inflammation.
发表文献
Brain Research
2023-11-14
Fndc5/irisin deficiency leads to dysbiosis of gut microbiota contributing to the depressive-like behaviors in mice
International Journal of Molecular Sciences
2023-02-18
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction
Theranostics
2021-01-20
NAD +-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin
1
发表文献
点击查看发表文献 >>
