L1td1-KO 基因敲除小鼠

1. Jin, Sang Woo, Seong, Youngmo, Yoon, Dayoung, Kwon, Young-Soo, Song, Hoseok. . Dissolution of ribonucleoprotein condensates by the embryonic stem cell protein L1TD1. In Nucleic acids research, 52, 3310-3326. doi:10.1093/nar/gkad1244. https://pubmed.ncbi.nlm.nih.gov/38165001/

2. Chakroborty, Deepankar, Emani, Maheswara Reddy, Klén, Riku, Lahesmaa, Riitta, Elo, Laura L. 2019. L1TD1 - a prognostic marker for colon cancer. In BMC cancer, 19, 727. doi:10.1186/s12885-019-5952-2. https://pubmed.ncbi.nlm.nih.gov/31337362/

3. McLaughlin, Richard N, Young, Janet M, Yang, Lei, Wichman, Holly A, Malik, Harmit S. 2014. Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency. In PLoS genetics, 10, e1004531. doi:10.1371/journal.pgen.1004531. https://pubmed.ncbi.nlm.nih.gov/25211013/

4. McKerrow, Wilson, Wang, Xuya, Mendez-Dorantes, Carlos, Boeke, Jef D, Fenyö, David. . LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint. In Proceedings of the National Academy of Sciences of the United States of America, 119, . doi:10.1073/pnas.2115999119. https://pubmed.ncbi.nlm.nih.gov/35169076/

5. Emani, Maheswara Reddy, Närvä, Elisa, Stubb, Aki, Elo, Laura L, Lahesmaa, Riitta. 2015. The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency. In Stem cell reports, 4, 519-28. doi:10.1016/j.stemcr.2015.01.014. https://pubmed.ncbi.nlm.nih.gov/25702638/

6. Wong, Raymond Ching-Bong, Ibrahim, Abel, Fong, Helen, Lock, Leslie F, Donovan, Peter J. 2011. L1TD1 is a marker for undifferentiated human embryonic stem cells. In PloS one, 6, e19355. doi:10.1371/journal.pone.0019355. https://pubmed.ncbi.nlm.nih.gov/21559406/

7. Altenberger, Corinna, Heller, Gerwin, Ziegler, Barbara, Zielinski, Christoph C, Zöchbauer-Müller, Sabine. 2017. SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers. In Molecular cancer, 16, 1. doi:10.1186/s12943-016-0568-5. https://pubmed.ncbi.nlm.nih.gov/28093071/

8. Santos, Márcia Cristina Teixeira, Silva, Patrícia Benites Gonçalves, Rodini, Carolina Oliveira, Moreira, José C F, Okamoto, Oswaldo Keith. 2015. Embryonic Stem Cell-Related Protein L1TD1 Is Required for Cell Viability, Neurosphere Formation, and Chemoresistance in Medulloblastoma. In Stem cells and development, 24, 2700-8. doi:10.1089/scd.2015.0052. https://pubmed.ncbi.nlm.nih.gov/26159230/

9. Närvä, Elisa, Rahkonen, Nelly, Emani, Maheswara Reddy, Rao, Anjana, Lahesmaa, Riitta. . RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation. In Stem cells (Dayton, Ohio), 30, 452-60. doi:10.1002/stem.1013. https://pubmed.ncbi.nlm.nih.gov/22162396/

10. Iwabuchi, Kumiko A, Yamakawa, Tatsuya, Sato, Yoshiko, Okita, Keisuke, Yamanaka, Shinya. 2011. ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency. In PloS one, 6, e20461. doi:10.1371/journal.pone.0020461. https://pubmed.ncbi.nlm.nih.gov/21637830/