Sgk2-KO 基因敲除小鼠

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2. Park, Chul-Hong, Moon, Jiyoung, Park, Minsung, Lee, Jisu, Chang, Ji Suk. 2021. Protein Kinase SGK2 Is Induced by the β3 Adrenergic Receptor-cAMP-PKA-PGC-1α/NT-PGC-1α Axis but Dispensable for Brown/Beige Adipose Tissue Thermogenesis. In Frontiers in physiology, 12, 780312. doi:10.3389/fphys.2021.780312. https://pubmed.ncbi.nlm.nih.gov/34899399/

3. Liu, Yang, Liu, Junying, Kong, Xin, Shao, Jianying, Jiang, Ziting. 2020. SGK2 is overexpressed in colon cancer and promotes epithelial-mesenchymal transition in colon cancer cells. In European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 46, 1912-1917. doi:10.1016/j.ejso.2020.06.002. https://pubmed.ncbi.nlm.nih.gov/32565024/

4. Liu, Junying, Zhang, Guangdong, Lv, Yanping, Kong, Xin, Yu, Yanzhang. . SGK2 promotes hepatocellular carcinoma progression and mediates GSK-3β/β-catenin signaling in HCC cells. In Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39, 1010428317700408. doi:10.1177/1010428317700408. https://pubmed.ncbi.nlm.nih.gov/28639896/

5. Liu, Y, Chen, J-B, Zhang, M, Zu, X-B, Liang, C-Z. . SGK2 promotes renal cancer progression via enhancing ERK 1/2 and AKT phosphorylation. In European review for medical and pharmacological sciences, 23, 2756-2767. doi:10.26355/eurrev_201904_17549. https://pubmed.ncbi.nlm.nih.gov/31002126/

6. Gotoh, Saki, Negishi, Masahiko. 2015. Statin-activated nuclear receptor PXR promotes SGK2 dephosphorylation by scaffolding PP2C to induce hepatic gluconeogenesis. In Scientific reports, 5, 14076. doi:10.1038/srep14076. https://pubmed.ncbi.nlm.nih.gov/26392083/

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8. Pao, Alan C, Bhargava, Aditi, Di Sole, Francesca, Moe, Orson W, Pearce, David. 2010. Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney. In American journal of physiology. Renal physiology, 299, F1496-506. doi:10.1152/ajprenal.00075.2010. https://pubmed.ncbi.nlm.nih.gov/20926631/