Lim2-KO 基因敲除小鼠

1. Wang, Xun, Qin, Yanli, Abudoukeremuahong, Aierxiding, Ding, Lin, Lin, Haotian. . Elongated axial length and myopia-related fundus changes associated with the Arg130Cys mutation in the LIM2 gene in four Chinese families with congenital cataracts. In Annals of translational medicine, 9, 235. doi:10.21037/atm-20-4275. https://pubmed.ncbi.nlm.nih.gov/33708862/

2. Irum, Bushra, Khan, Shahid Y, Ali, Muhammad, Eghrari, Allen O, Riazuddin, S Amer. 2016. Mutation in LIM2 Is Responsible for Autosomal Recessive Congenital Cataracts. In PloS one, 11, e0162620. doi:10.1371/journal.pone.0162620. https://pubmed.ncbi.nlm.nih.gov/27814360/

3. Pras, Eran, Levy-Nissenbaum, Etgar, Bakhan, Tangiz, Goldman, Boleslaw, Pras, Elon. 2002. A missense mutation in the LIM2 gene is associated with autosomal recessive presenile cataract in an inbred Iraqi Jewish family. In American journal of human genetics, 70, 1363-7. doi:. https://pubmed.ncbi.nlm.nih.gov/11917274/

4. Shiels, Alan, King, Jennifer M, Mackay, Donna S, Bassnett, Steven. . Refractive defects and cataracts in mice lacking lens intrinsic membrane protein-2. In Investigative ophthalmology & visual science, 48, 500-8. doi:. https://pubmed.ncbi.nlm.nih.gov/17251442/

5. Pei, Rui, Liang, Peng-Fei, Ye, Wei, Ma, Ji-Yuan, Zhou, Jian. 2020. A novel mutation of LIM2 causes autosomal dominant membranous cataract in a Chinese family. In International journal of ophthalmology, 13, 1512-1520. doi:10.18240/ijo.2020.10.02. https://pubmed.ncbi.nlm.nih.gov/33078099/