Hcrtr1-KO 基因敲除小鼠

1. Harro, Jaanus, Laas, Kariina, Eensoo, Diva, Mäestu, Jarek, Veidebaum, Toomas. 2019. Orexin/hypocretin receptor gene (HCRTR1) variation is associated with aggressive behaviour. In Neuropharmacology, 156, 107527. doi:10.1016/j.neuropharm.2019.02.009. https://pubmed.ncbi.nlm.nih.gov/30742846/

2. Pulver, Aleksander, Kiive, Evelyn, Kanarik, Margus, Harro, Jaanus. 2020. Association of orexin/hypocretin receptor gene (HCRTR1) with reward sensitivity, and interaction with gender. In Brain research, 1746, 147013. doi:10.1016/j.brainres.2020.147013. https://pubmed.ncbi.nlm.nih.gov/32652147/

3. Fukunaka, Yuko, Shinkai, Takahiro, Hwang, Rudi, Ohmori, Osamu, Nakamura, Jun. 2007. The orexin 1 receptor (HCRTR1) gene as a susceptibility gene contributing to polydipsia-hyponatremia in schizophrenia. In Neuromolecular medicine, 9, 292-7. doi:. https://pubmed.ncbi.nlm.nih.gov/17999203/

4. Dashti, Hassan S, Daghlas, Iyas, Lane, Jacqueline M, Garaulet, Marta, Saxena, Richa. 2021. Genetic determinants of daytime napping and effects on cardiometabolic health. In Nature communications, 12, 900. doi:10.1038/s41467-020-20585-3. https://pubmed.ncbi.nlm.nih.gov/33568662/

5. Kowalska, Marta, Kapelusiak-Pielok, Magdalena, Grzelak, Teresa, Kozubski, Wojciech, Dorszewska, Jolanta. 2018. The New *G29A and G1222A of HCRTR1, 5-HTTLPR of SLC6A4 Polymorphisms and Hypocretin-1, Serotonin Concentrations in Migraine Patients. In Frontiers in molecular neuroscience, 11, 191. doi:10.3389/fnmol.2018.00191. https://pubmed.ncbi.nlm.nih.gov/29922128/

6. Gottschalk, Michael G, Richter, Jan, Ziegler, Christiane, Höfler, Michael, Domschke, Katharina. 2019. Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes. In Translational psychiatry, 9, 75. doi:10.1038/s41398-019-0415-8. https://pubmed.ncbi.nlm.nih.gov/30718541/

7. Yay, Fatih, Ayan, Durmus. 2024. Bioinformatic analysis of neuropeptide related genes in patients diagnosed with invasive breast carcinoma. In Computers in biology and medicine, 183, 109304. doi:10.1016/j.compbiomed.2024.109304. https://pubmed.ncbi.nlm.nih.gov/39437604/