Tubb4b-KO 基因敲除小鼠

1. Maasz, Anita, Hadzsiev, Kinga, Ripszam, Reka, Gyenesei, Attila, Melegh, Bela. 2022. TUBB4B gene mutation in Leber phenotype of congenital amaurosis syndrome associated with early-onset deafness. In European journal of medical genetics, 65, 104471. doi:10.1016/j.ejmg.2022.104471. https://pubmed.ncbi.nlm.nih.gov/35240325/

2. Dodd, Daniel O, Mechaussier, Sabrina, Yeyati, Patricia L, Perrault, Isabelle, Mill, Pleasantine. 2024. Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. In Science (New York, N.Y.), 384, eadf5489. doi:10.1126/science.adf5489. https://pubmed.ncbi.nlm.nih.gov/38662826/

3. Yang, Zhenjie, Gao, Shanshan, Wong, Chi Chun, Kuang, Ming, Yu, Jun. 2023. TUBB4B is a novel therapeutic target in non-alcoholic fatty liver disease-associated hepatocellular carcinoma. In The Journal of pathology, 260, 71-83. doi:10.1002/path.6065. https://pubmed.ncbi.nlm.nih.gov/36787097/

4. Schijven, Dick, Soheili-Nezhad, Sourena, Fisher, Simon E, Francks, Clyde. 2024. Exome-wide analysis implicates rare protein-altering variants in human handedness. In Nature communications, 15, 2632. doi:10.1038/s41467-024-46277-w. https://pubmed.ncbi.nlm.nih.gov/38565598/