智鼠故事 
Trpc6-KO 基因敲除小鼠
复苏/繁育服务
产品名称
Trpc6-KO 基因敲除小鼠
产品编号
S-KO-05573
品系全称
C57BL/6NCya-Trpc6em1/Cya
品系背景
C57BL/6NCya
品系编号
KOCMP-22068-Trpc6-B6N-VA
品系状态
使用本品系发表的文献需注明： Trpc6-KO 基因敲除小鼠 mice (Strain S-KO-05573) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因全称
transient receptor potential cation channel, subfamily C, member 6
基因别称
TRP-6，Trrp6，mtrp6，LLHWJM002，LLHWJM003，LLHWJM004
染色体号
Chr 9 (Mouse)
NCBI ID
转录本 ID
NCBI: NM_013838 | Ensembl: ENSMUST00000050433
修饰方式
全身性基因敲除
靶向范围
Exon 5
敲除长度
~0.2 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:109523Mice homozygous for one null targeted mutation are viable and fertile and exhibit no overt abnormal phenotype. Another knockout results in an increase in thermal nociceptive response latency.
发表文献
Behavioral and Brain Functions : Bbf
2025-06-30
Chronic lipopolysaccharide exposure promotes cognitive impairments by activating TRPC6-AIM2 inflammasome signaling and the regulation of ginsenoside Rg1 in Trpc6−/− mice
Molecular Medicine Reports
2023-11-26
Trpc6 knockout protects against renal fibrosis by restraining the CN‑NFAT2 signaling pathway in T2DM mice
Experimental Neurology
2023-05
Trpc6 knockout improves behavioral dysfunction and reduces Aβ production by inhibiting CN-NFAT1 signaling in T2DM mice
1
发表文献
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