Sel1l-KO 基因敲除小鼠

1. Ji, Yewei, Luo, Yuan, Wu, Yating, Liang, Tingbo, Qi, Ling. 2023. SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool. In Nature cell biology, 25, 726-739. doi:10.1038/s41556-023-01138-4. https://pubmed.ncbi.nlm.nih.gov/37142791/

2. Gao, Yafeng, Li, Wenhui, Wang, Zhenghao, Zhang, Baojun, Zhang, Lianjun. 2023. SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis. In Cellular & molecular immunology, 20, 1232-1250. doi:10.1038/s41423-023-01078-x. https://pubmed.ncbi.nlm.nih.gov/37644166/

3. Liu, Qian, Chen, Jinyun, Wang, Jin, Wei, Chongjuan, Frazier, Marsha L. 2013. Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma. In Molecular carcinogenesis, 53, 711-21. doi:10.1002/mc.22023. https://pubmed.ncbi.nlm.nih.gov/23661430/

4. Wang, Jinyu, Li, Jing, Wu, Jingwen, Lu, Mengji, Zhang, Jiming. 2019. Host Gene SEL1L Involved in Endoplasmic Reticulum-Associated Degradation Pathway Could Inhibit Hepatitis B Virus at RNA, DNA, and Protein Levels. In Frontiers in microbiology, 10, 2869. doi:10.3389/fmicb.2019.02869. https://pubmed.ncbi.nlm.nih.gov/31921048/