Rrm1-KO 基因敲除小鼠

1. Altinkilic, Emre Murat, Isbir, Selim, Gormus, Uzay, Duman, Selvi, Isbir, Turgay. . RRM1, RRM2 and ERCC2 Gene Polymorphisms in Coronary Artery Disease. In In vivo (Athens, Greece), 30, 611-5. doi:. https://pubmed.ncbi.nlm.nih.gov/27566080/

2. Chen, Dar-Ren, Chuang, Chun-Yi, Wu, Buor-Chang, Peng, Yu-Hsien, Tsai, Hsiu-Ting. 2014. Association of novel gene polymorphisms RRM1 -756T>C and -269 C>A with breast cancer. In Journal of clinical laboratory analysis, 28, 287-93. doi:10.1002/jcla.21682. https://pubmed.ncbi.nlm.nih.gov/24578158/

3. Yang, Zituo, Wong, Sek Man, Yue, Gen Hua. 2021. Effects of rrm1 on NNV Resistance Revealed by RNA-seq and Gene Editing. In Marine biotechnology (New York, N.Y.), 23, 854-869. doi:10.1007/s10126-021-10068-x. https://pubmed.ncbi.nlm.nih.gov/34735644/

4. Mlak, Radosław, Powrózek, Tomasz, Brzozowska, Anna, Mazurek, Marcin, Małecka-Massalska, Teresa. . RRM1 gene expression evaluated in the liquid biopsy (blood cfRNA) as a non-invasive, predictive factor for radiotherapy-induced oral mucositis and potential prognostic biomarker in head and neck cancer patients. In Cancer biomarkers : section A of Disease markers, 22, 657-667. doi:10.3233/CBM-171082. https://pubmed.ncbi.nlm.nih.gov/29865035/

5. Jørgensen, Charlotte L T, Ejlertsen, Bent, Bjerre, Karsten D, Nielsen, Dorte L, Nielsen, Kirsten V. 2013. Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine. In BMC cancer, 13, 541. doi:10.1186/1471-2407-13-541. https://pubmed.ncbi.nlm.nih.gov/24215511/

6. Li, Borui, Xing, Faliang, Wang, Jingyi, Qin, Yi, Li, Zheng. 2024. YBX1 as a therapeutic target to suppress the LRP1-β-catenin-RRM1 axis and overcome gemcitabine resistance in pancreatic cancer. In Cancer letters, 602, 217197. doi:10.1016/j.canlet.2024.217197. https://pubmed.ncbi.nlm.nih.gov/39216548/

7. Jiang, Xinlei, Yu, Shangwei, Huang, Yuhan, He, Haohua, Fu, Haihui. 2024. Identification of the RRM1 gene family in rice (Oryza sativa) and its response to rice blast. In PeerJ, 12, e17668. doi:10.7717/peerj.17668. https://pubmed.ncbi.nlm.nih.gov/39076776/

8. Tian, Nannan, Zhou, Lei, Yang, Danni, Lü, Lin, Wu, Shaoyu. . [Silencing RRM1 gene reverses paclitaxel resistance in human breast cancer cell line MCF- 7/R by inducing cell apoptosis]. In Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 39, 304-312. doi:10.12122/j.issn.1673-4254.2019.03.08. https://pubmed.ncbi.nlm.nih.gov/31068300/

9. Wang, Lin-run, Zhang, Guo-bing, Chen, Jian, Wang, Yang, Shen Tu, Jian-zhong. . RRM1 gene expression in peripheral blood is predictive of shorter survival in Chinese patients with advanced non-small-cell lung cancer treated by gemcitabine and platinum. In Journal of Zhejiang University. Science. B, 12, 174-9. doi:10.1631/jzus.B1000197. https://pubmed.ncbi.nlm.nih.gov/21370501/

10. Volante, Marco, Terzolo, Massimo, Fassnacht, Martin, Papotti, Mauro, Berruti, Alfredo. 2012. Ribonucleotide reductase large subunit (RRM1) gene expression may predict efficacy of adjuvant mitotane in adrenocortical cancer. In Clinical cancer research : an official journal of the American Association for Cancer Research, 18, 3452-61. doi:10.1158/1078-0432.CCR-11-2692. https://pubmed.ncbi.nlm.nih.gov/22547773/