Trim40-KO 基因敲除小鼠

1. Kang, Sujin, Kim, Jaekyung, Park, Areum, Lee, Sungwook, Park, Boyoun. 2023. TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity. In Nature communications, 14, 700. doi:10.1038/s41467-023-36424-0. https://pubmed.ncbi.nlm.nih.gov/36755029/

2. Hu, Fangyu, Zhao, Lingling, Wang, Junyu, Huang, Chuanshu, Huang, Haishan. 2024. TRIM40 interacts with ROCK1 directly and inhibits colorectal cancer cell proliferation through the c-Myc/p21 axis. In Biochimica et biophysica acta. Molecular cell research, 1871, 119855. doi:10.1016/j.bbamcr.2024.119855. https://pubmed.ncbi.nlm.nih.gov/39357549/

3. Zhao, Chunyuan, Jia, Mutian, Song, Hui, Zhao, Wei, Cao, Xuetao. . The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I. In Cell reports, 21, 1613-1623. doi:10.1016/j.celrep.2017.10.020. https://pubmed.ncbi.nlm.nih.gov/29117565/

4. Shen, Yong, Tang, Kejun, Chen, Dongdong, Qian, Jing, Du, Yushen. . Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation. In Cell reports, 35, 109272. doi:10.1016/j.celrep.2021.109272. https://pubmed.ncbi.nlm.nih.gov/34161773/

5. Jia, Xiuzhi, Zhao, Chunyuan, Zhao, Wei. 2021. Emerging Roles of MHC Class I Region-Encoded E3 Ubiquitin Ligases in Innate Immunity. In Frontiers in immunology, 12, 687102. doi:10.3389/fimmu.2021.687102. https://pubmed.ncbi.nlm.nih.gov/34177938/