Pirt-KO 基因敲除小鼠

1. Gao, Xiao-Fei, Feng, Ji-Feng, Wang, Wei, Dong, Xin-Zhong, He, Cheng. 2015. Pirt reduces bladder overactivity by inhibiting purinergic receptor P2X3. In Nature communications, 6, 7650. doi:10.1038/ncomms8650. https://pubmed.ncbi.nlm.nih.gov/26151598/

2. Wang, Changming, Wang, Zhongli, Yang, Yan, Duan, Jinao, Tang, Zongxiang. 2015. Pirt contributes to uterine contraction-induced pain in mice. In Molecular pain, 11, 57. doi:10.1186/s12990-015-0054-x. https://pubmed.ncbi.nlm.nih.gov/26376721/

3. Jall, Sigrid, Finan, Brian, Collden, Gustav, Müller, Timo D, Clemmensen, Christoffer. 2019. Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice. In Molecular metabolism, 23, 75-81. doi:10.1016/j.molmet.2019.02.011. https://pubmed.ncbi.nlm.nih.gov/30902502/

4. Tang, Zongxiang, Kim, Andrew, Masuch, Thorsten, Wetzel, Christian, Dong, Xinzhong. . Pirt functions as an endogenous regulator of TRPM8. In Nature communications, 4, 2179. doi:10.1038/ncomms3179. https://pubmed.ncbi.nlm.nih.gov/23863968/