Pold2-KO 基因敲除小鼠

1. Givechian, Kevin B, Garner, Chad, Garban, Hermes, Rabizadeh, Shahrooz, Soon-Shiong, Patrick. 2018. CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma. In Oncotarget, 9, 29743-29752. doi:10.18632/oncotarget.25701. https://pubmed.ncbi.nlm.nih.gov/30038717/

2. Xu, Qingfu, Hu, Chengchen, Zhu, Yan, Jiang, Yugang, Li, Yunqing. 2020. ShRNA-based POLD2 expression knockdown sensitizes glioblastoma to DNA-Damaging therapeutics. In Cancer letters, 482, 126-135. doi:10.1016/j.canlet.2020.01.011. https://pubmed.ncbi.nlm.nih.gov/31954770/

3. Cong, Fengyun, Long, Junxian, Liu, Jun, Liu, Jinxin, Tang, Weizhong. 2022. An integrative analysis revealing POLD2 as a tumor suppressive immune protein and prognostic biomarker in pan-cancer. In Frontiers in genetics, 13, 877468. doi:10.3389/fgene.2022.877468. https://pubmed.ncbi.nlm.nih.gov/36081989/

4. Salehi, Zahra, Keramatipour, Mohammad, Talebi, Saeed, Sahraian, Mohammad Ali, Izad, Maryam. 2021. Exome sequencing reveals novel rare variants in Iranian familial multiple sclerosis: The importance of POLD2 in the disease pathogenesis. In Genomics, 113, 2645-2655. doi:10.1016/j.ygeno.2021.06.008. https://pubmed.ncbi.nlm.nih.gov/34116171/

5. Zhang, Jixiang, Xie, Shaojun, Cheng, Jinkui, Zhu, Jian-Kang, Gong, Zhizhong. 2016. The Second Subunit of DNA Polymerase Delta Is Required for Genomic Stability and Epigenetic Regulation. In Plant physiology, 171, 1192-208. doi:10.1104/pp.15.01976. https://pubmed.ncbi.nlm.nih.gov/27208288/