Pik3cd-KO 基因敲除小鼠

1. Poggi, Lucie, Chentout, Loïc, Lizot, Sabrina, Valton, Julien, Kracker, Sven. 2023. Rescuing the cytolytic function of APDS1 patient T cells via TALEN-mediated PIK3CD gene correction. In Molecular therapy. Methods & clinical development, 31, 101133. doi:10.1016/j.omtm.2023.101133. https://pubmed.ncbi.nlm.nih.gov/38152700/

2. Wang, Wenjie, Min, Qing, Lai, Nannan, Wang, Xiaochuan, Wang, Ji-Yang. 2022. Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene. In Frontiers in immunology, 13, 890073. doi:10.3389/fimmu.2022.890073. https://pubmed.ncbi.nlm.nih.gov/35799777/

3. Walsh, Zachary H, Shah, Parin, Kothapalli, Neeharika, Melms, Johannes C, Izar, Benjamin. 2024. Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens. In Nature biotechnology, , . doi:10.1038/s41587-024-02235-x. https://pubmed.ncbi.nlm.nih.gov/38783148/

4. Wang, Shengcai, Wang, Wei, Zhang, Xuexi, Tai, Jun, Ni, Xin. 2021. A somatic mutation in PIK3CD unravels a novel candidate gene for lymphatic malformation. In Orphanet journal of rare diseases, 16, 208. doi:10.1186/s13023-021-01782-9. https://pubmed.ncbi.nlm.nih.gov/33964933/

5. López-Nevado, Marta, González-Granado, Luis I, Ruiz-García, Raquel, Neth, Olaf, Allende, Luis M. 2021. Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management. In Frontiers in immunology, 12, 671755. doi:10.3389/fimmu.2021.671755. https://pubmed.ncbi.nlm.nih.gov/34447369/