P2rx7-KO 基因敲除小鼠

1. Gómez-Pinedo, U, Torre-Fuentes, L, Matías-Guiu, J A, Vidorreta-Ballesteros, L, Matías-Guiu, J. 2022. Exonic variants of the P2RX7 gene in familial multiple sclerosis. In Neurologia, , . doi:10.1016/j.nrleng.2022.12.001. https://pubmed.ncbi.nlm.nih.gov/36470550/

2. Shokoples, Brandon G, Berillo, Olga, Comeau, Kevin, Paradis, Pierre, Schiffrin, Ernesto L. 2023. P2RX7 gene knockout or antagonism reduces angiotensin II-induced hypertension, vascular injury and immune cell activation. In Journal of hypertension, 41, 1701-1712. doi:10.1097/HJH.0000000000003520. https://pubmed.ncbi.nlm.nih.gov/37796207/

3. Charras, Amandine, Hofmann, Sigrun R, Cox, Allison, Ferguson, Polly J, Hedrich, Christian M. 2024. P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO). In Journal of autoimmunity, 144, 103183. doi:10.1016/j.jaut.2024.103183. https://pubmed.ncbi.nlm.nih.gov/38401466/

4. Di Virgilio, Francesco, Dal Ben, Diego, Sarti, Alba Clara, Giuliani, Anna Lisa, Falzoni, Simonetta. . The P2X7 Receptor in Infection and Inflammation. In Immunity, 47, 15-31. doi:10.1016/j.immuni.2017.06.020. https://pubmed.ncbi.nlm.nih.gov/28723547/

5. Vereczkei, Andrea, Abdul-Rahman, Omar, Halmai, Zsuzsa, Faludi, Gabor, Nemoda, Zsofia. 2019. Association of purinergic receptor P2RX7 gene polymorphisms with depression symptoms. In Progress in neuro-psychopharmacology & biological psychiatry, 92, 207-216. doi:10.1016/j.pnpbp.2019.01.006. https://pubmed.ncbi.nlm.nih.gov/30664971/

6. Kristof, Zsuliet, Eszlari, Nora, Sutori, Sara, Bagdy, Gyorgy, Gonda, Xenia. 2021. P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms. In PloS one, 16, e0252766. doi:10.1371/journal.pone.0252766. https://pubmed.ncbi.nlm.nih.gov/34111150/