Mdh2-KO 基因敲除小鼠

1. Cascón, Alberto, Comino-Méndez, Iñaki, Currás-Freixes, María, Urioste, Miguel, Robledo, Mercedes. 2015. Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene. In Journal of the National Cancer Institute, 107, . doi:10.1093/jnci/djv053. https://pubmed.ncbi.nlm.nih.gov/25766404/

2. Chen, Yong-Hong, Liu, Shu-Jing, Gao, Mei-Mei, Yi, Yong-Hong, Long, Yue-Sheng. 2017. MDH2 is an RNA binding protein involved in downregulation of sodium channel Scn1a expression under seizure condition. In Biochimica et biophysica acta. Molecular basis of disease, 1863, 1492-1499. doi:10.1016/j.bbadis.2017.04.018. https://pubmed.ncbi.nlm.nih.gov/28433711/

3. Ait-El-Mkadem, Samira, Dayem-Quere, Manal, Gusic, Mirjana, Fuchs, Sabine A, Paquis-Flucklinger, Véronique. 2016. Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. In American journal of human genetics, 100, 151-159. doi:10.1016/j.ajhg.2016.11.014. https://pubmed.ncbi.nlm.nih.gov/27989324/