Mettl1-KO 基因敲除小鼠

1. Huang, Manling, Long, Jianting, Yao, Zhijia, Xu, Lixia, Kuang, Ming. . METTL1-Mediated m7G tRNA Modification Promotes Lenvatinib Resistance in Hepatocellular Carcinoma. In Cancer research, 83, 89-102. doi:10.1158/0008-5472.CAN-22-0963. https://pubmed.ncbi.nlm.nih.gov/36102722/

2. Ying, Xiaoling, Liu, Bixia, Yuan, Zusen, Luo, Junhang, Ji, Weidong. . METTL1-m7 G-EGFR/EFEMP1 axis promotes the bladder cancer development. In Clinical and translational medicine, 11, e675. doi:10.1002/ctm2.675. https://pubmed.ncbi.nlm.nih.gov/34936728/

3. Chen, Jie, Li, Kang, Chen, Jianwen, Wang, Anxun, Chen, Demeng. 2022. Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression. In Cancer communications (London, England), 42, 223-244. doi:10.1002/cac2.12273. https://pubmed.ncbi.nlm.nih.gov/35179319/

4. Huang, Ying, Ma, Jieyi, Yang, Cuiyun, Lin, Shuibin, Huang, Libin. 2022. METTL1 promotes neuroblastoma development through m7G tRNA modification and selective oncogenic gene translation. In Biomarker research, 10, 68. doi:10.1186/s40364-022-00414-z. https://pubmed.ncbi.nlm.nih.gov/36071474/