1. Heinen, Charlotte A, de Vries, Emmely M, Alders, Mariëlle, van Trotsenburg, A S Paul, Fliers, Eric. 2018. Mutations in IRS4 are associated with central hypothyroidism. In Journal of medical genetics, 55, 693-700. doi:10.1136/jmedgenet-2017-105113. https://pubmed.ncbi.nlm.nih.gov/30061370/
2. Hao, Peiqi, Huang, Ying, Peng, Jun, An, Su, Xu, Tian-Rui. 2021. IRS4 promotes the progression of non-small cell lung cancer and confers resistance to EGFR-TKI through the activation of PI3K/Akt and Ras-MAPK pathways. In Experimental cell research, 403, 112615. doi:10.1016/j.yexcr.2021.112615. https://pubmed.ncbi.nlm.nih.gov/33894221/
3. Panagopoulos, Ioannis, Andersen, Kristin, Brunetti, Marta, Micci, Francesca, Heim, Sverre. . Pathogenetic Dichotomy in Angioleiomyoma. In Cancer genomics & proteomics, 20, 556-566. doi:10.21873/cgp.20405. https://pubmed.ncbi.nlm.nih.gov/37889065/
4. Li, Xinchun, Zhong, Li, Wang, Zhuo, Zhang, Hongyu, Kang, Tiebang. 2018. Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway. In Theranostics, 8, 3643-3653. doi:10.7150/thno.26021. https://pubmed.ncbi.nlm.nih.gov/30026872/
5. He, Yang, Ma, Yue, Zhu, Ye, Tong, Zhongsheng, Zhao, Weipeng. 2024. HDAC inhibitors target IRS4 to enhance anti‑AR therapy in AR‑positive triple‑negative breast cancer. In International journal of oncology, 64, . doi:10.3892/ijo.2024.5613. https://pubmed.ncbi.nlm.nih.gov/38214343/
6. Ikink, Gerjon J, Boer, Mandy, Bakker, Elvira R M, Hilkens, John. 2016. IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation. In Nature communications, 7, 13567. doi:10.1038/ncomms13567. https://pubmed.ncbi.nlm.nih.gov/27876799/
7. Karrman, Kristina, Isaksson, Margareth, Paulsson, Kajsa, Johansson, Bertil. 2011. The insulin receptor substrate 4 gene (IRS4) is mutated in paediatric T-cell acute lymphoblastic leukaemia. In British journal of haematology, 155, 516-9. doi:10.1111/j.1365-2141.2011.08709.x. https://pubmed.ncbi.nlm.nih.gov/21517825/