智鼠故事 
C57BL/6JCya-Inhaem1/Cya 全身性基因敲除小鼠
复苏/繁育服务
产品名称
Inha-KO
产品编号
S-KO-02662
品系全称
C57BL/6JCya-Inhaem1/Cya
品系背景
C57BL/6JCya
品系编号
KOCMP-16322-Inha-B6J-VA
品系状态
使用本品系发表的文献需注明： Inha-KO mice (Strain S-KO-02662) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
--
NCBI ID
染色体号
Chr 1
NCBI RefSeq
NM_010564
Ensembl ID
ENSMUST00000037330
修饰方式
全身性基因敲除
靶向范围
Exon 2
敲除长度
~2.4 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:96569Mutant mice develop gonadal sex cord-stromal tumors with nearly 100% penetrance and develop cachexia-like symptoms. The wasting syndrome is not observed in gonadectomized mutant mice, which develop adrenal tumors. Homozygous inhibition of inhibin activity leads to increased ovulation but reduced embryo/fetal/newborn survival of offspring of affected mothers, while heterozygote mothers show increased fecundity.
