Il11-KO 基因敲除小鼠

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2. Schafer, Sebastian, Viswanathan, Sivakumar, Widjaja, Anissa A, Sin, Kenny Y K, Cook, Stuart A. 2017. IL-11 is a crucial determinant of cardiovascular fibrosis. In Nature, 552, 110-115. doi:10.1038/nature24676. https://pubmed.ncbi.nlm.nih.gov/29160304/

3. Moon, Eui Jung, Mello, Stephano S, Li, Caiyun G, Attardi, Laura D, Giaccia, Amato J. 2021. The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling. In Nature communications, 12, 4308. doi:10.1038/s41467-021-24631-6. https://pubmed.ncbi.nlm.nih.gov/34262028/

4. Widjaja, Anissa A, Singh, Brijesh K, Adami, Eleonora, Schafer, Sebastian, Cook, Stuart A. 2019. Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis. In Gastroenterology, 157, 777-792.e14. doi:10.1053/j.gastro.2019.05.002. https://pubmed.ncbi.nlm.nih.gov/31078624/