Ube4a-KO 基因敲除小鼠

1. Contino, Gianmarco, Amati, Francesca, Pucci, Sabina, Spagnoli, Luigi Giusto, Novelli, Giuseppe. . Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissues. In Gene, 328, 69-74. doi:. https://pubmed.ncbi.nlm.nih.gov/15019985/

2. Hu, Xianyan, Zou, Rong, Zhang, Zaihui, Zhang, Xiaoli, Zhang, Zai-Rong. 2023. UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage. In Biochimica et biophysica acta. Gene regulatory mechanisms, 1866, 194937. doi:10.1016/j.bbagrm.2023.194937. https://pubmed.ncbi.nlm.nih.gov/37084817/

3. Melo, Uirá Souto, Bonner, Devon, Kent Lloyd, Kevin C, Kok, Fernando, Byers, Heather M. 2021. Biallelic UBE4A loss-of-function variants cause intellectual disability and global developmental delay. In Genetics in medicine : official journal of the American College of Medical Genetics, 23, 661-668. doi:10.1038/s41436-020-01047-z. https://pubmed.ncbi.nlm.nih.gov/33420346/

4. Xie, Canbin, Long, Fei, Li, Liang, Hu, Gui, Lin, Changwei. 2022. PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability. In Cell death & disease, 13, 128. doi:10.1038/s41419-022-04564-8. https://pubmed.ncbi.nlm.nih.gov/35136024/

5. Sun, Yanan, Jia, Xiaopeng, Gao, Qiang, Liu, Xing, Hou, Lianguo. 2016. The ubiquitin ligase UBE4A inhibits prostate cancer progression by targeting interleukin-like EMT inducer (ILEI). In IUBMB life, 69, 16-21. doi:10.1002/iub.1585. https://pubmed.ncbi.nlm.nih.gov/27862841/

6. Zhu, Xiaoqin, Zeng, Chuanfei, Yu, Baoping. 2024. White adipose tissue in metabolic associated fatty liver disease. In Clinics and research in hepatology and gastroenterology, 48, 102336. doi:10.1016/j.clinre.2024.102336. https://pubmed.ncbi.nlm.nih.gov/38604293/

7. Feng, Ying, Jin, Ming-Yue, Liu, Dong-Wei, Wei, Li. 2019. Bone morphogenetic protein (BMP) 7 expression is regulated by the E3 ligase UBE4A in diabetic nephropathy. In Archives of physiology and biochemistry, 126, 416-419. doi:10.1080/13813455.2018.1551905. https://pubmed.ncbi.nlm.nih.gov/30663414/

8. Carén, H, Holmstrand, A, Sjöberg, R-M, Martinsson, T. 2006. The two human homologues of yeast UFD2 ubiquitination factor, UBE4A and UBE4B, are located in common neuroblastoma deletion regions and are subject to mutations in tumours. In European journal of cancer (Oxford, England : 1990), 42, 381-7. doi:. https://pubmed.ncbi.nlm.nih.gov/16386891/