Cyp2b19-KO 基因敲除小鼠

1. Du, Liping, Yermalitsky, Valery, Ladd, Patricia A, Mernaugh, Raymond, Keeney, Diane S. . Evidence that cytochrome P450 CYP2B19 is the major source of epoxyeicosatrienoic acids in mouse skin. In Archives of biochemistry and biophysics, 435, 125-33. doi:. https://pubmed.ncbi.nlm.nih.gov/15680914/

2. Keeney, D S, Skinner, C, Travers, J B, King, L E, Waterman, M R. . Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. In The Journal of biological chemistry, 273, 32071-9. doi:. https://pubmed.ncbi.nlm.nih.gov/9822682/

3. Ladd, Patricia A, Du, Liping, Capdevila, Jorge H, Mernaugh, Raymond, Keeney, Diane S. 2003. Epoxyeicosatrienoic acids activate transglutaminases in situ and induce cornification of epidermal keratinocytes. In The Journal of biological chemistry, 278, 35184-92. doi:. https://pubmed.ncbi.nlm.nih.gov/12840027/