Hmgcl-flox 基因敲除小鼠

1. Sun, Yanfei, Mu, Guangjing, Zhang, Xuehai, Han, Mingzhi, Huang, Bin. . Metabolic modulation of histone acetylation mediated by HMGCL activates the FOXM1/β-catenin pathway in glioblastoma. In Neuro-oncology, 26, 653-669. doi:10.1093/neuonc/noad232. https://pubmed.ncbi.nlm.nih.gov/38069906/

2. Gouirand, Victoire, Gicquel, Tristan, Lien, Evan C, Vander Heiden, Matthew G, Vasseur, Sophie. 2022. Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. In The EMBO journal, 41, e110466. doi:10.15252/embj.2021110466. https://pubmed.ncbi.nlm.nih.gov/35307861/

3. Qin, Chunyu, Wang, Haibo, Peng, Wei, Zhong, Jincheng, Wang, Hui. 2023. Circular RNA mapping reveals CircCWC22 as a MiR-3059-x sponge in yak fat deposition by regulating HMGCL. In International journal of biological macromolecules, 257, 128531. doi:10.1016/j.ijbiomac.2023.128531. https://pubmed.ncbi.nlm.nih.gov/38042314/