Osbpl2-flox 基因敲除小鼠

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6. Wang, Hongshun, Lin, Changsong, Yao, Jun, Xing, Guangqian, Cao, Xin. 2019. Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity. In Cell death & disease, 10, 627. doi:10.1038/s41419-019-1858-9. https://pubmed.ncbi.nlm.nih.gov/31427568/

7. Zhang, Cui, Zhang, Hongdu, Zhang, Min, Xing, Guangqian, Cao, Xin. 2019. OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway. In Experimental cell research, 383, 111512. doi:10.1016/j.yexcr.2019.111512. https://pubmed.ncbi.nlm.nih.gov/31356817/

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