智鼠故事 
Hnrnpk-flox 基因敲除小鼠
复苏/繁育服务
产品名称
Hnrnpk-flox 基因敲除小鼠
产品编号
S-CKO-18253
品系全称
C57BL/6JCya-Hnrnpkem1flox/Cya
品系背景
C57BL/6JCya
品系编号
CKOCMP-15387-Hnrnpk-B6J-VB
品系状态
使用本品系发表的文献需注明： Hnrnpk-flox 基因敲除小鼠 mice (Strain S-CKO-18253) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因全称
heterogeneous nuclear ribonucleoprotein K
基因别称
KBBP，NOVA，Hnrpk
染色体号
Chr 13 (Mouse)
NCBI ID
转录本 ID
NCBI: NM_001301341 | Ensembl: ENSMUST00000116403
修饰方式
条件性基因敲除
靶向范围
Exon 4~7
敲除长度
~3.7 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:99894Male mice homozygous for a conditional allele activated in male germ cells exhibit small testes, reduced body size, meiotic arrest at prophase, increased male germ cell apoptosis, and infertility.
发表文献
Nature Communications
2025-07-31
The long non-coding RNA RSDR protects against acute kidney injury in mice by interacting with hnRNPK to regulate DHODH-mediated ferroptosis
Cell Death & Differentiation
2023-08
Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf
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