Metrn-flox 基因敲除小鼠

1. Jung, Tae Woo, Lee, Sung Hoon, Kim, Hyoung-Chun, Shin, Yong Kyoo, Jeong, Ji Hoon. 2018. METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice. In Experimental & molecular medicine, 50, 1-11. doi:10.1038/s12276-018-0147-5. https://pubmed.ncbi.nlm.nih.gov/30213948/

2. Cao, Qinchen, Shi, Yonggang, Wang, Xinxin, Zhai, Guan, Zhang, Mingzhi. 2019. Circular METRN RNA hsa_circ_0037251 Promotes Glioma Progression by Sponging miR-1229-3p and Regulating mTOR Expression. In Scientific reports, 9, 19791. doi:10.1038/s41598-019-56417-8. https://pubmed.ncbi.nlm.nih.gov/31875034/

3. Xu, Xin, Zhang, Chihao, Xia, Yan, Yu, Jiwei. 2019. Over expression of METRN predicts poor clinical prognosis in colorectal cancer. In Molecular genetics & genomic medicine, 8, e1102. doi:10.1002/mgg3.1102. https://pubmed.ncbi.nlm.nih.gov/31859449/

4. Wang, Zhaolu, Andrade, Nuno, Torp, Malene, Jørgensen, Jesper Roland, Lindvall, Olle. 2011. Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis. In Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 32, 387-98. doi:10.1038/jcbfm.2011.156. https://pubmed.ncbi.nlm.nih.gov/22044868/

5. Garcia-Beltran, Cristina, Navarro-Gascon, Artur, López-Bermejo, Abel, Ibáñez, Lourdes, Villarroya, Francesc. 2023. Meteorin-like levels are associated with active brown adipose tissue in early infancy. In Frontiers in endocrinology, 14, 1136245. doi:10.3389/fendo.2023.1136245. https://pubmed.ncbi.nlm.nih.gov/36936161/