Hilpda-flox 基因敲除小鼠

1. Povero, Davide, Chen, Yongbin, Johnson, Scott M, Razidlo, Gina L, Liu, Jun. 2023. HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia. In Journal of hepatology, 79, 378-393. doi:10.1016/j.jhep.2023.03.041. https://pubmed.ncbi.nlm.nih.gov/37061197/

2. Zhang, Yue, Pang, Chen, Zhang, Chi, Xie, Ganfeng, Ou, Juanjuan. 2023. HILPDA-mediated lipidomic remodelling promotes radiotherapy resistance in nasopharyngeal carcinoma by accelerating mitophagy. In Cellular and molecular life sciences : CMLS, 80, 242. doi:10.1007/s00018-023-04891-9. https://pubmed.ncbi.nlm.nih.gov/37552373/

3. Wang, Sheng, Ye, Wufei, Yang, Kui, Lv, Xiongwen, Luan, Jiajie. 2024. Prognostic Hypoxia-Angiogenesis-Related Gene Signature in Hepatocellular Carcinoma, in Which HILPDA Contributes to Tumor Progression. In Journal of inflammation research, 17, 5663-5683. doi:10.2147/JIR.S476388. https://pubmed.ncbi.nlm.nih.gov/39219818/

4. Gong, Zheng, Li, Qing, Shi, Jiayuan, Shultz, Leonard D, Ren, Guangwen. . Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells. In Cell metabolism, 34, 1960-1976.e9. doi:10.1016/j.cmet.2022.11.003. https://pubmed.ncbi.nlm.nih.gov/36476935/