Rpe-flox 基因敲除小鼠

1. Brown, Emily E, DeWeerd, Alexander J, Ildefonso, Cristhian J, Lewin, Alfred S, Ash, John D. 2019. Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors. In Redox biology, 24, 101201. doi:10.1016/j.redox.2019.101201. https://pubmed.ncbi.nlm.nih.gov/31039480/

2. Tangeman, Jared A, Pérez-Estrada, J Raúl, Van Zeeland, Emily, Liang, Chun, Del Rio-Tsonis, Katia. 2022. A Stage-Specific OTX2 Regulatory Network and Maturation-Associated Gene Programs Are Inherent Barriers to RPE Neural Competency. In Frontiers in cell and developmental biology, 10, 875155. doi:10.3389/fcell.2022.875155. https://pubmed.ncbi.nlm.nih.gov/35517508/

3. Orozco, Luz D, Chen, Hsu-Hsin, Cox, Christian, van Lookeren Campagne, Menno, Hackney, Jason A. . Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration. In Cell reports, 30, 1246-1259.e6. doi:10.1016/j.celrep.2019.12.082. https://pubmed.ncbi.nlm.nih.gov/31995762/