Fndc4-flox 基因敲除小鼠

1. Xu, Xiaoming, Peng, Lu, Xia, Yunlong, Yan, Wenjun, Tao, Ling. 2024. Fibronectin type III domain containing 4 alleviates myocardial ischemia/reperfusion injury via the Nrf2-dependent antioxidant pathway. In Free radical biology & medicine, 224, 256-271. doi:10.1016/j.freeradbiomed.2024.08.033. https://pubmed.ncbi.nlm.nih.gov/39197598/

2. Lv, Zheng-Tao, Liang, Shuang, Chen, Kun, Liao, Hui, Chen, An-Min. 2018. FNDC4 Inhibits RANKL-Induced Osteoclast Formation by Suppressing NF-κB Activation and CXCL10 Expression. In BioMed research international, 2018, 3936257. doi:10.1155/2018/3936257. https://pubmed.ncbi.nlm.nih.gov/29977911/

3. Georgiadi, Anastasia, Lopez-Salazar, Valeria, Merahbi, Rabih El-, Blüher, Matthias, Herzig, Stephan. 2021. Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. In Nature communications, 12, 2999. doi:10.1038/s41467-021-22579-1. https://pubmed.ncbi.nlm.nih.gov/34016966/

4. Bosma, Madeleen, Gerling, Marco, Pasto, Jenny, Boström, Elisabeth Almer, Boström, Pontus Almer. 2016. FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice. In Nature communications, 7, 11314. doi:10.1038/ncomms11314. https://pubmed.ncbi.nlm.nih.gov/27066907/

5. Li, Hongwu, Yan, Xiaofei, Ou, Shaowu. 2022. Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization. In Cancer cell international, 22, 273. doi:10.1186/s12935-022-02688-7. https://pubmed.ncbi.nlm.nih.gov/36056336/

6. Li, Ningxin, Li, Huan, Zhou, Shufen, Liu, Yahui, Ma, Zhanchuan. 2023. Overexpression of FNDC4 constrains ovarian cancer progression by promoting cell apoptosis and inhibiting cell growth. In Journal of Cancer, 14, 3416-3428. doi:10.7150/jca.88964. https://pubmed.ncbi.nlm.nih.gov/38021165/

7. Camacho, Mercedes, León, Xavier, Pujol, Albert, Quer, Miquel, García, Jacinto. 2022. Prognostic value of transcriptional expression of fibronectin type III domain-containing 4 (FNDC4) in head and neck carcinoma patients treated with chemoradiotherapy. In Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 24, 2175-2180. doi:10.1007/s12094-022-02870-3. https://pubmed.ncbi.nlm.nih.gov/35752749/

8. Wuensch, Tilo, Wizenty, Jonas, Quint, Janina, Pratschke, Johann, Aigner, Felix. 2019. Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer. In Gastroenterology research and practice, 2019, 3784172. doi:10.1155/2019/3784172. https://pubmed.ncbi.nlm.nih.gov/31093274/

9. Martin, Paul J, Storer, Barry E, Levine, David M, Hansen, John A. . Genetic variants associated with inflammatory bowel disease and gut graft-versus-host disease. In Blood advances, 5, 4456-4464. doi:10.1182/bloodadvances.2021004959. https://pubmed.ncbi.nlm.nih.gov/34535014/

10. Wang, Yongchun, McKelvey, Brittany A, Liu, Zhiyang, Zeiger, Martha A, Umbricht, Christopher B. 2021. Retrospective analysis of cancer-specific gene expression panel for thyroid fine needle aspiration specimens. In Journal of cancer research and clinical oncology, 147, 2983-2991. doi:10.1007/s00432-021-03706-3. https://pubmed.ncbi.nlm.nih.gov/34165589/